Home All anti-PXN antibodies
Anti-PXN Antibody Y113
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
|A synthetic peptide corresponding to residues in N-terminus of human Paxillin was used as immunogen. This antibody detects alpha, beta and gamma isoforms of Paxillin.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1:5,000-10,000; IHC: 1: 100; ICC: 1:250; IP: 1:200
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens paxillin (PXN), transcript variant 1|
|Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) (1). Paxillin plays a significant role in integrin signaling and the tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization (2). Paxillin is phosphorylated by focal adhesion kinase (FAK) at Tyr118 (3). It has been found that phosphorylation of paxillin at both Tyr118 and Tyr31 is essential for MM1 cancer cell migration (4). |
EGFR1 Signaling Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis on Hela cell lysate using anti-Paxilin (N-term), dilution 1:10,000.
Immunohistochemical analysis of paraffin-embedded breast carcinoma using anti-Paxillin (N-term).
Immunofluorescent staining of HeLa cells using anti-Paxillin (N-term).