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Anti-CREB1 Antibody E306

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues before DNA binding motif of human CREB was used as immunogen. This antibody can also recognize the splice isoform of CREB. Predicted to cross-react with bovine, based on sequence homology.
Clone Name	E306	Isotype	IgG
Species Reactivity	Human, Mouse	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:500-1,000; IHC: 1:250-500; ICC: 1:250-500; FC: 1:40; IP: 1:80
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant B
Alternative Name	CREB
Database Link	NP_604391
Function	CREB is a transcription factor protein that binds the cAMP response element (CRE), thereby stimulating transcription of this sequence. CREB plays a role in propagating numerous extracellular signals to the nuclues (1-3). CREB is activated by phosphorylation at the Ser133 position by various signaling pathways, and some of the kinases involved in phosphorylating CREB at Ser133 are p90RSK, MSK, CaMKIV and MAPKAPK-2 (1-3).
Related Pathway	Adipogenesis EGFR1 Signaling Pathway Melanogenesis

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • CREB1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • CREB1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Creb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • CREB1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Creb1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant B as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant B as transfection-ready DNA Related cDNA Clones • Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant B as transfection-ready DNA • Homo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant B as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)