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Home Antibody All anti-PDGFRB antibodies

Anti-PDGFRB Antibody Y92

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300416
  • Rabbit Monoclonal Antibody against PDGFRB (Clone Y92)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400921) , 20ug
100ul $325 In Stock
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WB(1)
IHC(1)
IF(2)
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Also for PDGFRB (NM_002609)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in C-terminus of human PDGF receptor- ß was used as immunogen. The antibody does not cross-react with other CSF-1/PDGF receptor family members.
Clone NameY92 IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1: 10,000; IHC: 1: 100; ICC: 1: 100; IP: 1:30
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction

Reference Data

Target NameHomo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)
Alternative NameCD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Database LinkNP_002600
FunctionHuman platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-a and PDGF receptor-ß. PDGF receptor-ß can only bind two specific PDGF isoforms, PDGF-ß and PDGF-? (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.
Related Pathway
Cytokine-cytokine receptor interaction
Focal Adhesion
MAPK signaling pathway

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WB Image
Western blot - PDGF Receptor beta antibody [Y92]; Anti-PDGF Receptor beta antibody [Y92] + NIH 3T3 cell lysate.Predicted band size : 124 kDa.Observed band size : 175 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.
IF Image
Immunocytochemistry/ Immunofluorescence - PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.

 

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