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Anti-IL6 Antibody E457
|A recombinant human IL-6 protein was used as immunogen.|
||Lot dependent; please refer to CoA along with shipment
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens interleukin 6 (IL6)|
|BSF2; HGF; HSF; IFNB2; IL-6|
|Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway
Senescence and Autophagy
Toll-like receptor signaling pathway
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Western blot - IL6 antibody [E457]; Anti-IL6 antibody [E457].Predicted band size : 24 kDa.Observed band size : 22 kDa .
Western blot - IL6 antibody [E457]; Anti-IL6 antibody [E457] at 1/1000 dilution + Media from cultured human prostate tissue at 30 µg.Secondary.An HRP-conjugated anti-rabbit IgG polyclonal (1/1000).Predicted band size : 24 kDa.Observed band size : 24 kDa.Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.This image is courtesy of an anonymous customer.