Homo sapiens keratin 8 (KRT8), transcript variant 2
Synonyms:
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser73 of human Cytokeratin 8 was used as immunogen. The antibody only detects Keratin 8 phosphorylated on Serine 73.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Keratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the ove
Related Pathway
EGFR1 Signaling Pathway
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Western blot analysis on A431 cell lysates using anti-Phospho-Keratin 8 (pS73), dilution 1:10,000. Cell lysates were either (1) untreated or (2) treated with EGF.
