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Anti-CAV1 Antibody E249
Also for CAV1 (NM_001753)
|A synthetic peptide corresponding to residues near C-terminus of human Caveolin-1 was used as immunogen. The antibody should recognize both alpha and beta form of Caveolin-1.|
||0.5~1.0 mg/ml (Lot Dependent)
||ICC/IF: Use at an assay dependent dilution; IHC-P: 1:250; ICC: 1:100; WB: 1:1000 - 1:10000
|Does not react with Rat. Is unsuitable for Flow Cyt or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), transcript variant 1|
|BSCL3; CGL3; MSTP085; PPH3; VIP21|
|Caveolins make up a family of proteins that are principal structural components of hairpin-like domains in the plasma membrane (1). It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Three members of caveolins (caveolin-1, -2 and -3) have been identified, possessing different tissue distributions (2). Caveolins interact with multiple signaling molecules, such as the G-protein alpha subunit (1), tyrosine kinase receptors, PKCs, Src family tyrosine kinases and eNOS (2,3). Caveolin-1 has been implicated in the pathogenesis of mammary epithelial cell hyperplasia (4).|
EGFR1 Signaling Pathway
TGF Beta Signaling Pathway
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Western blot - Caveolin 1 antibody [E249]; Anti-Caveolin 1 antibody [E249] + A431 cell lysate.Predicted band size : 20 kDa.Observed band size : 23 kDa .Additional bands at : 22 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human urinary bladder tissue, staining Caveolin 1 with ab32577 at 1/250 dilution.
Immunohistochemistry (Paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung tissue, staining Caveolin 1 with ab32577 at 1/250µg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Caveolin 1 antibody [E249]; Immunohistochemical analysis of developing Human lung tissue, staining Caveolin 1 with ab32577 at 1/250 dilution.