Homo sapiens signal sequence receptor, alpha (SSR1)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SSR1.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. (Protein A or G Sepharose)
Guaranteed Application *
WB: 1:50~100; ELISA: 1: 1,000
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
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(LEFT)Western blot analysis of SSR1 (arrow) using rabbit polyclonal SSR1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SSR1 gene (Lane 2). (RIGHT)Western blot analysis of anti-SSR1 Antibody (C-term) in T47D cell line lysates (35ug/lane). SSR1 (arrow) was detected using the purified polyclonal antibody.
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