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Also for STK11 (NM_000455)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region encoding isoleucine at position 29 of human STK11 Antibody .|
||WB: 1: 1000
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|Homo sapiens serine/threonine kinase 11 (STK11)|
|hLKB1; LKB1; PJS|
|STK11 encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.|
TGF Beta Signaling Pathway
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HEK293T cells were transfected with the pCMV6-XL5 control or pCMV-STK11 (SC119871) cDNA for 72 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STK11 Rabbit polyclonal Ab. The size markers are shown in numbers and the correct 49kDa STK11 protein is indicated by an arrow.