Home Antibody All anti-CSF1R antibodies
Also for CSF1R (NM_005211)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 955~972 of human CSF1R.|
||0.5~1.0 mg/ml (Lot Dependent)
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens colony stimulating factor 1 receptor (CSF1R), transcript variant 1|
|C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R|
|CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy.|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
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Western blot analysis of anti-CSF1R Pab (TA300025) in human placenta. CSF1R (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.