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Home Antibody All anti-CSF1R antibodies

Anti-CSF1R Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300025 Rabbit Polyclonal Antibody against CSF1R 100ug $325 In Stock
LC401594 CSF1R HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for CSF1R (NM_005211)
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OriGene Data

ImmunogenThis MCSF Receptor (CSF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-971 amino acids from the C-terminal region of human MCSF Receptor (CSF1R).
Clone Name IsotypeIg
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB: 1:1000, FC: 1:10~50, IHC: 1:10~50
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens colony stimulating factor 1 receptor (CSF1R), transcript variant 1
Alternative NameC-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Database LinkNP_005202
Entrez Gene 1436 Human
FunctionCSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
Related PathwayProtein KinaseTransmembraneDruggable Genome Cytokine-cytokine receptor interactionEndocytosisHematopoietic cell lineagePathways in cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of anti-CSF1R Pab (Cat. #TA300025) in human placenta. CSF1R (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

WB Image
Western blot analysis of CSF1R (arrow) using rabbit polyclonal CSF1R Antibody (C-term)(Cat.#TA300025). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CSF1R gene (Lane 2) (Origene Technologies).

IHC Image
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CSF1R Antibody (C-term) (Cat.#TA300025), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

FC Image
MCSF Receptor (CSF1R) Antibody (C-term) (Cat. #TA300025) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


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