CDC2 (CDK3) complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in cell cycle control. CDK3 can phosphorylate histone H1 and interacts with an unknown type of cyclin.
Hedgehog signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway
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HEK293T cells were transfected with the pCMV6-XL5 control or pCMV-Cdc2 (SC111605) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-pCdc2-T161 Rabbit polyclonal Ab. The size markers are shown in numbers and the correct 35 kDa phospho-Cdc2 protein is indicated by an arrow.
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