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Home Antibody All anti-SYPL1 antibodies

Anti-SYPL1 Antibody

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SKU Description Amount Price Availability*  
TA306817 Rabbit Polyclonal SYPL1 Antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSYPL1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human SYPL1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens synaptophysin-like 1 (SYPL1), transcript variant 1
Alternative NameH-SP1; SYPL
Database LinkNP_006745
Entrez Gene 6856 Human
Entrez Gene 366595 Rat
FunctionThe synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles. This antibody will not recognize synaptophysin of SYPL2. Two isoforms of SYPL1 are known to exist; this antibody will only recognize the longer isoform.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of SYPL1 in human brain tissue lysate with SYPL1 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
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