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Home All anti-SYP antibodies
Anti-SYP Antibody EP1098Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
OriGene Data
| A synthetic peptide corresponding to residues in human Synaptophysin was used as an immunogen. |
| EP1098Y |
IgG |
| Human, Mouse, Rat |
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| WB, IHC, IF |
WB: 1:200,000; IHC: 1:250 500; ICC: 1:250 500; FC: 1:20; IP: 1:50 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens synaptophysin (SYP) |
| MRXSYP |
| NP_003170 |
| Synaptophysin is an integral membrane protein of small synaptic vesicles in brain and endocrine cells (1). Synaptophysin (syp I) is a synaptic vesicle membrane protein that constitutes approximately 7% of the total vesicle protein. Multiple lines of evidence implicate syp I in a number of nerve terminal functions (2). Synaptophysin is one of the most abundant membrane proteins of small synaptic vesicles. In mature nerve terminals it forms a complex with the vesicular membrane protein synaptobrevin, which appears to modulate synaptobrevin's interaction with the plasma membrane-associated proteins syntaxin and SNAP25 to form the SNARE complex as a prerequisite for membrane fusion. It has been shown that synaptobrevin is preferentially cleaved by tetanus toxin while bound to synaptophysin or when existing as a homodimer (3). data suggest that synaptophysin is released from the Golgi apparatus in a vesicular form, after glycosylation, and is then transported to nerve endings by a mechanism which requires integrity of microtubules (4). |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on rat brain membrane using anti-Synaptophysin, dilution 1:200,000.
IHC Image
Immunohistochemical staining of paraffin-embedded human medulloblastoma using anti-Synaptophysin.
IF Image
Immunofluorescent staining of PC12 cells using anti-Synaptophysin.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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