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Anti-SYN1 Phospho Antibody EP2162Y
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Also for SYN1 (NM_006950)
|A synthetic phospho-peptide corresponding to residues surrounding serine 9 of human synapsin I protein.|
|Human, Mouse, Rat
||WB: 1:1000 - 5000; IHC: 1:250; ICC: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens synapsin I (SYN1), transcript variant Ia|
|SYN1a; SYN1b; SYNI|
|This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]. |
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Western blot analysis on human brain tissue lysates using anti-Phospho-Synapsin I (pS9) RabMAb (TA303711), 1:5000 dilution. Cells were either (A) untreated (B) treated with AP
Immunohistochemical analysis of paraffin-embedded human brain using anti-phospho Synapsin (pS9) RabMAb (TA303711).