Home Antibody All anti-SWAP70 antibodies
Also for SWAP70 (NM_015055)
| Peptide with sequence C-EEREKNWKEKKTTE, from the C Terminus of the protein sequence according to NP_055870.2.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat
||ELISA: 1:64,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens SWAP switching B-cell complex 70kDa subunit (SWAP70), transcript variant 1|
Entrez Gene 23075 Human
Entrez Gene 20947 Mouse
Entrez Gene 293410 Rat
|Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity)|
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TA302776 staining (2µg/ml) of Daudi lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.