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Home Antibody All anti-SUMO2 antibodies

Anti-SUMO2 Antibody EPR4602

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307648
  • Rabbit monoclonal antibody against SUMO-2/3(clone EPR4602)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC423659) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for SUMO2 (NM_001005849)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SUMO-2/3 was used as an immunogen.
Clone NameEPR4602 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens small ubiquitin-like modifier 2 (SUMO2), transcript variant 2
Alternative NameHSMT3; Smt3A; SMT3B; SMT3H2; SUMO3
Database LinkNP_001005849
FunctionSUMO proteins and ubiquitin posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (1). SUMO-2/3 is a ubiquitin-like protein that can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer (2). Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I; it can be promoted by an E3 ligase (2). Moreover, SUMO-2/3 is expressed predominantly in the liver (2).
Related Pathway
Wnt Signaling Pathway

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WB Image
Western blot - Anti-Sumo 2+3 antibody [EPR4602]; All lanes : Anti-Sumo 2+3 antibody [EPR4602] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : 293T cell lysate.Lane 4 : SW480 cell lysate.Lane 5 : HL60 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 11 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sumo 2+3 antibody [EPR4602]; TA307648 at 1/100 dilution, staining Sumo 2+3 in Human colon by Immunohistochemistry, Paraffin-embedded tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Sumo 2 antibody [EPR4602]; TA307648 at 1/100 diltuion, staining Sumo 2+3 in Human hepatocellular carcinoma by Immunohistochemistry, Paraffin-embedded tissue.

 

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