Home Antibody All anti-SUCLA2 antibodies
Also for SUCLA2 (NM_003850)
|Recombinant fragment corresponding to a region within amino acids 138 and 416 of SUCLA2 (Uniprot ID#Q9P2R7)|
|Human, Mouse (Predicted: Rat, Xenopus laevis, Zebrafish, Bovine, Xenopus tropicalis)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:20000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (88%), Xenopus laevis (85%), Zebrafish (81%), Bovine (92%), Xenopus tropicalis (83%)
|Homo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2)|
|A-BETA; MTDPS5; SCS-betaA|
Entrez Gene 8803 Human
Entrez Gene 20916 Mouse
Entrez Gene 361071 Rat
|Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]|
| Citrate cycle (TCA cycle)Propanoate metabolismMetabolic pathways|
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Sample (20 ug of whole cell lysate). A: mouse brain. 10% SDS PAGE. TA308975 diluted at 1:20000.
Sample (30 ug of whole cell lysate). A: Hep G2 . B: Molt-4 . 10% SDS PAGE. TA308975 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SUCLA2(TA308975) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed A431, using SUCLA2(TA308975) antibody at 1:200 dilution.