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Home Antibody All anti-SUCLA2 antibodies

Anti-SUCLA2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308975
  • Rabbit Polyclonal antibody to SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401267) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
IF(1)
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Also for SUCLA2 (NM_003850)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 138 and 416 of SUCLA2 (Uniprot ID#Q9P2R7)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Xenopus laevis, Zebrafish, Bovine, Xenopus tropicalis) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:20000
Predicted MW Explanation 50kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (88%), Xenopus laevis (85%), Zebrafish (81%), Bovine (92%), Xenopus tropicalis (83%)

Reference Data

Target NameHomo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2)
Alternative NameA-BETA; MTDPS5; SCS-betaA
Database LinkNP_003841
Entrez Gene 8803 Human
Entrez Gene 20916 Mouse
Entrez Gene 361071 Rat
FunctionSuccinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]
Related Pathway Citrate cycle (TCA cycle)Propanoate metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (20 ug of whole cell lysate). A: mouse brain. 10% SDS PAGE. TA308975 diluted at 1:20000.
WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . B: Molt-4 . 10% SDS PAGE. TA308975 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SUCLA2(TA308975) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using SUCLA2(TA308975) antibody at 1:200 dilution.

 

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