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Also for STK24 (NM_001032296)
|Synthetic peptide corresponding to a region within amino acids 137 and 231 of MST3 (Uniprot ID#Q9Y6E0)|
|Human (Predicted: Bovine, Chicken, Mouse, Rhesus Monkey, Xenopus laevis, Xenopus Tropicalis)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens serine/threonine kinase 24 (STK24), transcript variant 2|
|HEL-S-95; MST3; MST3B; STE20; STK3|
Entrez Gene 8428 Human
Entrez Gene 223255 Mouse
Entrez Gene 697841 Monkey
|The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM]|
|Protein KinaseDruggable Genome |
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STK24 antibody [N2C1], Internal detects STK24 protein by western blot analysis. A. 50 ug rat brain lysate/extract. 10 % SDS-PAGE. STK24 antibody [N2C1], Internal (TA308491) dilution: 1:1000
Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308491 diluted at 1:1000.
STK24 antibody [N2C1], Internal detects STK24 protein at cytosol and nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. STK24 antibody [N2C1], Internal (TA308491) dilution: 1:250.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using STK24(TA308491) antibody at 1:200 dilution.