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Home Antibody All anti-STK11 antibodies

Anti-STK11 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300047
  • STK11 Antibody (N-term I29) Rabbit Polyclonal Antibody (Pab)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424705) , 20ug Explanation
100ug 325 3-7 Days
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WB(2)
IHC(1)
IF(1)
FC(1)

OriGene Data

ImmunogenThis STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).
Clone Name IsotypeIg
Species ReactivityHuman (Predicted: Mouse, Rat, Chicken, Xenopus) Concentration0.25 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsIHC: 1:50~100, WB: 1:1000, FC: 1:10~50, IF: 1:10~50
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens serine/threonine kinase 11 (STK11)
Alternative NamehLKB1; LKB1; PJS
Database LinkNP_000446
Entrez Gene 6794 Human
Entrez Gene 20869 Mouse
Entrez Gene 314621 Rat
FunctionSTK11 encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
Related PathwayProtein KinaseDruggable Genome mTOR signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody
WB Image
STK11 Antibody (I29) (Cat. #TA300047) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the STK11 antibody detected the STK11 protein (arrow).
IHC Image
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
IF Image
Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29)(Cat#TA300047) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
FC Image
STK11 (LKB1) Antibody (N-term I29) (Cat. #TA300047) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

 

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