Home Antibody All anti-STK11 antibodies
Also for STK11 (NM_000455)
|This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).|
|Human (Predicted: Mouse, Rat, Chicken, Xenopus)
|WB, IHC, IF, FC
||IHC: 1:50~100, WB: 1:1000, FC: 1:10~50, IF: 1:10~50
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is purified through a protein A column, followed by peptide affinity purification.
|Homo sapiens serine/threonine kinase 11 (STK11)|
|hLKB1; LKB1; PJS|
|STK11 encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.|
TGF Beta Signaling Pathway
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Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody
STK11 Antibody (I29) (Cat. #TA300047) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the STK11 antibody detected the STK11 protein (arrow).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29)(Cat#TA300047) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
STK11 (LKB1) Antibody (N-term I29) (Cat. #TA300047) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.