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Home Antibody All anti-STAT6 antibodies

Anti-STAT6 Antibody YE361

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300446
  • Rabbit Monoclonal Antibody against STAT6 (Clone YE361)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401100) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for STAT6 (NM_003153)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human Stat-6 was used as immunogen. The antibody does not cross-react with other Stat family members.
Clone NameYE361 IsotypeIgG fraction
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:2000; IHC-P: Use at an assay dependent concentration; ICC/IF: 1:100; IP: 1:80
BufferDoes not react with Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2
Alternative NameD12S1644; IL-4-STAT; STAT6B; STAT6C
Database LinkNP_003144
Entrez Gene 6778 Human
Entrez Gene 20852 Mouse
FunctionJanus family tyrosine kinases (Jaks) and signal transducers and activators of transcription (STATs) are involved in mediating gene expression in response to cytokines and interferons. Jaks associate with cytokine receptors; upon ligand binding, Jaks phosphorylate the receptor. The phosphorylated receptors are bound by SH2-containing proteins, one class of which is the STATs. Activated STATs, then, translocate to the nucleus to mediate gene transcription (1,2). Stat-6 is tyrosine phosphorylated in response to cellular interaction with IL-3 and IL-4 (3,4).
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - STAT6 antibody [YE361]; Anti-STAT6 antibody [YE361] at 1/1000 dilution + NIH 3T3 cell lysate.Predicted band size : 94 kDa.Observed band size : 100 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - STAT6 antibody [YE361]; Immunohistochemical staining of paraffin-embedded human skin carcinoma using TA300446 at 1/100 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - STAT6 antibody [YE361]; Immunofluorescent staining of HeLa cells using TA300446 at 1/100 dilution.

 

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