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Home Antibody All anti-STAT5B antibodies

Anti-STAT5B Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA318912 Rabbit polyclonal anti-Stat5 antibody 100ug $325 3-7 Days
LC415754 STAT5B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for STAT5B (NM_012448)
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OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 777 of human Stat5
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 2-10 ug/ml, IHC: 20ug/ml, IP: 20ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS).
Purification Affinity purified

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 5B (STAT5B)
Alternative NameSTAT5
Database LinkNP_036580
Entrez Gene 6777 Human
Entrez Gene 20851 Mouse
Entrez Gene 25126 Rat
FunctionMembrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3ß appears to be activated by both while Stat3a is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome ErbB signaling pathwayChemokine signaling pathwayJak-STAT signaling pathwayPathways in cancerChronic myeloid leukemiaAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Stat-5 expression in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2).


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