Anti-STAT5A Antibody, clone 1H9

Also for STAT5A (NM_003152)

OriGene Data

Immunogen	Full length human recombinant protein of human STAT5A (NP_003143) produced in HEK293T cell.
Clone Name	clone 1H9	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, FC	Suggested Dilutions	WB 1:500~2000, FLOW 1:100
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens signal transducer and activator of transcription 5A (STAT5A)
Alternative Name	MGF; STAT5
Database Link	NP_003143
Function	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq].
Related Pathway	Adipogenesis EGFR1 Signaling Pathway Jak-STAT signaling pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT5A (RC205753, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT5A.

FC Image

HEK293T cells transfected with either RC205753 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-STAT5A antibody(TA502813), and then analyzed by flow cytometry.

FC Image

Flow cytometric Analysis of Jurkat cells, using anti-STAT5A antibody(TA502813),(Red), compared to a nonspecific negative control antibody,(Blue).

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Anti-STAT5A TrueMAB Antibody clone 1H9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data