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Home Antibody All anti-STAT5A antibodies

Anti-STAT5A TRUEMAB Antibody Clone OTI10H1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502735 STAT5A mouse monoclonal antibody, clone OTI10H1 (formerly 10H1) 100ul $325 In Stock
LC418866 STAT5A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502735 Carrier-free (BSA/glycerol-free) STAT5A mouse monoclonal antibody, clone OTI10H1 (formerly 10H1) 100ug $450 3 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
FC(2)
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Also for STAT5A (NM_003152)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human STAT5A (NP_003143) produced in HEK293T cell.
Clone NameClone OTI10H1 IsotypeIgG2b
Species ReactivityHuman Concentration0.33 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 90.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 5A (STAT5A), transcript variant 2
Alternative NameMGF; STAT5
Database LinkNP_003143
Entrez Gene 6776 Human
FunctionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome ErbB signaling pathwayJak-STAT signaling pathwayPathways in cancerChronic myeloid leukemiaAcute myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT5A (RC205753, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT5A.
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Anti-STAT5A mouse monoclonal antibody (TA502735) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY STAT5A(RC205753).
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Flow cytometric Analysis of Hela cells, using anti-STAT5A antibody(TA502735),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-STAT5A antibody(TA502735),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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