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Anti-STAT4 TRUEMAB Antibody clone 4H6
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for STAT4 (NM_003151)
|Full length human recombinant protein of human STAT4 (NP_003142) produced in HEK293T cell. |
|WB, IHC, FC
|| WB 1:2000, IHC 1:150, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1|
Entrez Gene 6775 Human
|The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug |
|Transcription FactorsDruggable Genome Jak-STAT signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT4 (RC206892 , Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT4.
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-STAT4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502940)
HEK293T cells transfected with either RC206892 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-STAT4 antibody(TA502940), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-STAT4 antibody(TA502940),(Red), compared to a nonspecific negative control antibody,(Blue).