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Home Antibody All anti-STAT4 antibodies

Anti-STAT4 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324197
  • Anti-STAT4 (Phospho-Tyr693) Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for STAT4 (NM_003151)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of tyrosine 693 (K-G-Y(p)-V-P) derived from Human STAT4.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500-1000, IHC: 1:50-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1
Alternative NameSLEB11
Database LinkNP_003142
Entrez Gene 6775 Human
Entrez Gene 20849 Mouse
Entrez Gene 367264 Rat
FunctionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Related Pathway
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 86 kDa . Positive control: HepG2 cells treated with IL-4 lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: HepG2 cells treated with IL-4 lysate Lane2: Untreated HepG2 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
IHC Image
Predicted cell location: Cytoplasm; Nucleus. Positive control: Human breast carcinoma tissue. Recommended dilution: 1/ 50-100 The image on the left is immunohistochemistry of paraffin-embedded human breast carcinoma tissue using STAT4 (Phospho-Tyr693) antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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