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Home Antibody All anti-STAT1 antibodies

Anti-STAT1 Antibody EPYR2154

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307007
  • Rabbit monoclonal antibody against Stat-1 (clone EPYR2154 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC408329) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for STAT1 (NM_139266)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Stat-1 was used as an immunogen.
Clone NameEPYR2154 IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsFC: 1:50, IP: 1:50, WB: 1:1000 - 2000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant beta
Alternative NameCANDF7; ISGF-3; STAT91
Database LinkNP_644671
FunctionStat-1 is a latent transcription factor that functions both as a signal transducer in the cytoplasm and an activator of transcription in the nucleus. Stat-1 is one of seven members of the Signal transducer and activators of transcription (Stats) family (1). Stat-1 is activated by a different number of ligands; IFN?, IFN?, EGF, PDGF and IL6 (2-3). Upon tyrosine phosphorylation, Stat-1 dimerize with Stat-2 and associates with ISGF3/IR9 to form the ISGF3 complex (4). This activation subsequently allows the complex to translocate to the nucleus & bind specific enhancer elements. Additional complexes can form upon IFN stimulation (1).
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - STAT1 antibody [EPYR2154]; All lanes : Anti-STAT1 antibody [EPYR2154] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293 cell lysate.Lane 3 : NIH-3T3 cell lysate.Lane 4 : A431 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 87 kDa.Observed band size : 91 kDa .

 

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