Home Antibody All anti-STARD3 antibodies
Anti-STARD3 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for STARD3 (NM_006804)
|DNA immunization. This antibody is specific for the C Terminus Region of the target protein.|
||ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:10-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens StAR-related lipid transfer (START) domain containing 3 (STARD3), transcript variant 1|
|CAB1; es64; MLN64|
Entrez Gene 10948 Human
|The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN 64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN 64 are deleted, the resulting N-218 MLN 64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN 64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN 64 is similar to the organization of StAR. However, as MLN 64 never enters the mitochondria, the protease-resistant domain of MLN 64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Antibody dilution: 1:100. Image and statement courtesy of the Human Protein Atlas (HPA).