OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-STARD3 antibodies
UltraMAB

Anti-STARD3 GAT Antibody Polyclonal

Generated by Genomic Immunization

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590564
  • Rabbit Polyclonal STARD3 Antibody
50ug 325 In Stock
Add to Shopping Cart
IHC(1)
ELISA(1)
spacer
Also for STARD3 (NM_006804)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.15mg/ml
Guaranteed Application *ELISA, IHC Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:10-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens StAR-related lipid transfer (START) domain containing 3 (STARD3), transcript variant 1
Alternative NameCAB1; es64; MLN64
Database LinkNP_006795
Entrez Gene 10948 Human
FunctionThe steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN 64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN 64 are deleted, the resulting N-218 MLN 64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN 64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN 64 is similar to the organization of StAR. However, as MLN 64 never enters the mitochondria, the protease-resistant domain of MLN 64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA Image
ELISA: STARD3 Antibody
IHC Image
Immunohistochemistry: STARD3 Antibody - Normal and malignant tissues generally displayed moderate to strong cytoplasmic immunoreactivity. Strong positivity was noted in both hepatocellular and cholangiocarcinomas though normal hepatocytes were moderately stained. Other strongly positive cancers included endometrial, urothelial, renal and gastro-intestinal cancers. Other cancers were generally moderately positive. Image and statement courtesy of the Human Protein Atlas (HPA).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title