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Anti-SSRP1 Antibody EPR7894
Also for SSRP1 (NM_003146)
|A synthetic peptide corresponding to residues in human SSRP1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; FC: 1:100 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens structure specific recognition protein 1 (SSRP1)|
|FACT; FACT80; T160|
Entrez Gene 6749 Human
Entrez Gene 20833 Mouse
Entrez Gene 81785 Rat
|SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box that most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63 (1).|
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Western blot - Anti-SSRP1 antibody [EPR7894]; All lanes : Anti-SSRP1 antibody [EPR7894] at 1/10000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : MOLT4 cell lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 81 kDa.
Other-Anti-SSRP1 antibody [EPR7894](TA310878); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-SSRP1 antibody [EPR7894]; TA310878, at 1/100 dilution, staining SSRP1 in permeabilized MOLT4 cells by Flow cytometry (red) or Rabbit IgG negative control (green).