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Anti-SRP19 Antibody EPR8378
Also for SRP19 (NM_003135)
|A synthetic peptide corresponding to residues in human SRP19 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC, IF
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens signal recognition particle 19kDa (SRP19), transcript variant 1|
|signal recognition particle 19kDa|
Entrez Gene 6728 Human
Entrez Gene 66384 Mouse
Entrez Gene 291685 Rat
|SRP19 is an RNA-binding component of the Signal recognition particle (SRP), consisting of a 7S RNA molecule of 300 nucleotides and six protein subunits (SRP72, SRP68, SRP54, SRP19, SRP14, and SRP9), and it plays a role in the assembly of SRP (1, 2). It interacts with the major groove of the helix 6 tetraloop and the minor groove of the helix 8 tetraloop, and it clamps the tetraloops of two branched helices in the S-domain of SRP RNA (1). SRP19 is also directly bound and efficiently imported into the nuclei in vitro by two members of the importin beta family of transport receptors, importin 8 and transportin (3).|
| Protein export|
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Western blot - Anti-SRP19 antibody [EPR8378]; All lanes : Anti-SRP19 antibody [EPR8378] at 1/10000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Daudi cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 16 kDa.
Other-Anti-SRP19 antibody [EPR8378](TA310875); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SRP19 antibody [EPR8378]; Immunohistochemical analysis of paraffin-embedded Human spleen tissue labelling SRP19 with TA310875 at 1/100 dilution.
Immunocytochemistry/ Immunofluorescence - Anti-SRP19 antibody [EPR8378]; Immunofluorescence analysis of HepG2 cells labelling SRP19 with TA310875 at 1/100 dilution.