Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
SRP19 is an RNA-binding component of the Signal recognition particle (SRP), consisting of a 7S RNA molecule of 300 nucleotides and six protein subunits (SRP72, SRP68, SRP54, SRP19, SRP14, and SRP9), and it plays a role in the assembly of SRP (1, 2). It interacts with the major groove of the helix 6 tetraloop and the minor groove of the helix 8 tetraloop, and it clamps the tetraloops of two branched helices in the S-domain of SRP RNA (1). SRP19 is also directly bound and efficiently imported into the nuclei in vitro by two members of the importin beta family of transport receptors, importin 8 and transportin (3).
Related Pathway
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