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Home Antibody All anti-SRD5A2 antibodies

Anti-SRD5A2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302992 Goat Polyclonal Antibody against SRD5A2 100ug $325 3-7 Days
LC400128 SRD5A2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)

OriGene Data

Immunogen Peptide with sequence QVQCQQSPVLAG, from the N Terminus of the protein sequence according to NP_000339.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.3-1.0 µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (SRD5A2)
Alternative NameMGC138457
Database LinkNP_000339
Entrez Gene 6716 Human
FunctionThis gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Androgen and estrogen metabolismProstate cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302992 (0.3µg/ml) staining of human testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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