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Home Antibody All anti-SPR antibodies

Anti-SPR TRUEMAB Antibody clone 1F4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501984
  • SPR mouse monoclonal antibody, clone 1F4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401086) , 20ug Explanation
100ul
30ul
325 In Stock
CF501984
  • Carrier-free (BSA/glycerol-free) SPR mouse monoclonal antibody, clone 1F4
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IF(1)
FC(3)
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Also for SPR (NM_003124)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.
Clone Nameclone 1F4 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:500~2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 27.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)
Alternative NameSDR38C1
Database LinkNP_003115
Entrez Gene 6697 Human
Entrez Gene 705317 Monkey
FunctionThis gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq].
Related PathwayDruggable Genome Folate biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
IF Image
Anti-SPR mouse monoclonal antibody (TA501984) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPR(RC205679).
FC Image
HEK293T cells transfected with either RC205679 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SPR antibody(TA501984), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Hela cells, using anti-SPR antibody(TA501984),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-SPR antibody(TA501984),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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