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Anti-SPR TRUEMAB Antibody Clone OTI2F7
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Full length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.|
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)|
Entrez Gene 6697 Human
Entrez Gene 705317 Monkey
|This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq]. |
|Druggable Genome Folate biosynthesisMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SPR monoclonal antibody.