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Home Antibody All anti-SPR antibodies

Anti-SPR TRUEMAB Antibody Clone OTI2F7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501982 SPR mouse monoclonal antibody, clone OTI2F7 (formerly 2F7) 100ul $325 In Stock
LC401086 SPR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501982 Carrier-free (BSA/glycerol-free) SPR mouse monoclonal antibody, clone OTI2F7 (formerly 2F7) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human SPR (NP_003115) produced in HEK293T cell.
Clone NameClone OTI2F7 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.45 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:500~2000,
Predicted MW Explanation 27.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)
Alternative NameSDR38C1
Database LinkNP_003115
Entrez Gene 6697 Human
Entrez Gene 705317 Monkey
FunctionThis gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq].
Related PathwayDruggable Genome Folate biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPR (RC205679, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPR.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SPR monoclonal antibody.
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