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Home Antibody All anti-SPG7 antibodies

Anti-SPG7 TRUEMAB Antibody Clone OTI1D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504421 SPG7 mouse monoclonal antibody, clone OTI1D3 (formerly 1D3) 100ul $325 In Stock
LC401085 SPG7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504421 Carrier-free (BSA/glycerol-free) SPG7 mouse monoclonal antibody, clone OTI1D3 (formerly 1D3) 100ug $450 3-4 weeks
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WB(1)
IHC(3)
FC(1)

OriGene Data

ImmunogenHuman recombinant protein fragement corresponding to amino acids 300-573 of human SPG7(NP_003110) produced in E.coli.
Clone NameClone OTI1D3 IsotypeIgG1
Species ReactivityHuman Concentration0.53 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 88.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens spastic paraplegia 7 (pure and complicated autosomal recessive) (SPG7), transcript variant 1
Alternative NameCAR; CMAR; PGN; SPG5C
Database LinkNP_003110
Entrez Gene 6687 Human
FunctionThis gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq].
Related PathwayTransmembraneProtease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPG7 (RC206340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPG7.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SPG7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504421)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SPG7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504421)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-SPG7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504421)
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HEK293T cells transfected with either RC206340 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SPG7 antibody(TA504421), and then analyzed by flow cytometry.
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