Homo sapiens Sp1 transcription factor (SP1), transcript variant 2
Synonyms:
specificity protein 1; Sp1 transcription factor
Immunogen
Peptide with sequence CSRIESPNENSNNSQ, from the internal region of the protein sequence according to NP_612482.2.
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clone Name
Isotype
Goat IgG
Species Reactivity
Human
Concentration
0.5 mg/ml
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. (Protein A or G Sepharose)
Guaranteed Application *
WB
Suggested Dilutions
ELISA: 1:16,000. WB: 0.3-1µg/ml.
Background
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
TGF Beta Signaling Pathway
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TA303043 staining (0.3µg/ml) of Hela lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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