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Home Antibody All anti-SOX2 antibodies

Anti-SOX2 Antibody EPR3130

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307387
  • Rabbit monoclonal antibody against SOX2 (clone EPR3130 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401083) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(3)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SOX2 was used as an immunogen.
Clone NameEPR3130 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC-P: 1:50 - 1:100; WB: 1:500 - 1:1000; IP: 1:10
Predicted MW Explanation 34 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or ICC/IF.

Reference Data

Target NameHomo sapiens SRY (sex determining region Y)-box 2 (SOX2)
Alternative NameANOP3; MCOPS3
Database LinkNP_003097
Entrez Gene 6657 Human
FunctionSOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. It is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach (1). SOX2 is necessary for regulating multiple transcription factors that affect Oct3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression (2).
Related PathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsEmbryonic stem cellsInduced pluripotent stem cellsTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SOX2 antibody [EPR3130]; Anti-SOX2 antibody [EPR3130] at 1/500 dilution + NCCIT cell lysate at 10 ug.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 34 kDa.Observed band size : 35 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX2 antibody [EPR3130]; Immunohistochemical analysis of Formalin-fixed, paraffin embedded Human fetal brain tissue labelling SOX2 with TA307387 at 1/50 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX2 antibody [EPR3130]; Immunohistochemical analysis of Formalin-fixed, paraffin embedded Human glioma tissue labelling SOX2 with TA307387 at 1/50 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX2 antibody [EPR3130]; Immunohistochemical analysis of Formalin-fixed, paraffin embedded Human brain tissue staining SOX2 with TA307387 at 1/50 dilution.

 

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