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Also for SOX2 (NM_003106)
|SOX2 recombinant protein is used to produce this monoclonal antibody.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:200~2000; IHC: 1:50~100; ELISA: 1: 1,0000;
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. (Protein A or G Sepharose)
|Homo sapiens SRY (sex determining region Y)-box 2 (SOX2)|
|SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.|
Wnt Signaling Pathway
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(LEFT)Western blot analysis of anti-SOX2 Monoclonal Antibody by SOX2 recombinant protein. SOX2(arrow) was detected using the purified Mab. (RIGHT)Western blot analysis of SOX2 (arrow) using mouse monoclonal SOX2 antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SOX2 gene (Lane 2) (Origene Technologies)
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOX2 Monoclonal Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.