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Home Antibody All anti-SORL1 antibodies

Anti-SORL1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305805
  • Goat Anti-SORL1 / LR11 (C Terminus) Antibody
100ug 325 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-TGFSDDVPMVIA, from the C Terminus of the protein sequence according to NP_003096.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.3-1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens sortilin-related receptor, L(DLR class) A repeats containing (SORL1)
Alternative NameC11orf32; gp250; LR11; LRP9; SORLA; SorLA-1
Database LinkNP_003096
FunctionThis gene encodes a protein that belongs to the families of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, of low density lipoprotein receptor (LDLR) proteins, and of fibronectin type III repeats proteins. In addition to VPS10, LDLR and fibronectin type 3 domains, this protein also includes an epidermal growth factor precursor-like module, a single transmembrane segment and a cytoplasmic tail with features similar to endocytosis- and sorting-competent receptors. Members of the VPS10 domain-containing receptor family are large with many exons but the CDS lengths are usually less than 3700 nt; this gene is an exception to the pattern with a CDS length greater than 6600 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. The encoded protein is mainly intracellular and localizes in the paranuclear compartment. It is synthesized as a preproprotein, and when the propeptide is still attached, no binding occurs to the VPS10 domain. This gene is strongly expressed in the central nervous system. [provided by RefSeq].
Related Pathway

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WB Image
TA305805 (0.3ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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