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Anti-SOD1 TRUEMAB Antibody clone 8B10
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for SOD1 (NM_000454)
|Full length human recombinant protein of human SOD1 (NP_000445) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:1000~2000, IHC 1:50, FLOW 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens superoxide dismutase 1, soluble (SOD1)|
|ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD|
Entrez Gene 6647 Human
|The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]. |
|Druggable Genome Amyotrophic lateral sclerosis (ALS)Huntington's diseasePrion diseases|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOD1 (RC200725, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOD1.
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-SOD1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500495)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500495)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500495)
HEK293T cells transfected with either RC200725 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SOD1 antibody(TA500495), and then analyzed by flow cytometry.