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Home Antibody All anti-SOCS1 antibodies

Anti-SOCS1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302691
  • Goat Polyclonal Antibody against SOCS1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401230) , 20ug
100ug 325 In Stock
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WB(1)
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Also for SOCS1 (NM_003745)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-VLRDYLSSFPFQI, from the C Terminus of the protein sequence according to NP_003736.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Mouse, Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-2 µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens suppressor of cytokine signaling 1 (SOCS1)
Alternative NameCIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3
Database LinkNP_003736
FunctionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq].
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302691 staining (2µg/ml) of mouse spleen lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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