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Home Antibody All anti-SNAI2 antibodies

Anti-SNAI2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306360 Rabbit Polyclonal Slug Antibody 100ug $325 In Stock
LC401070 SNAI2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
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Also for SNAI2 (NM_003068)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSlug antibody was raised against a 14 amino acid peptide from near the center of human Slug .
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens snail family zinc finger 2 (SNAI2)
Alternative NameSLUG; SLUGH1; SNAIL2; WS2D
Database LinkNP_003059
Entrez Gene 6591 Human
Entrez Gene 20583 Mouse
FunctionSlug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family. Slug antibody has no cross-reactivity to Snail protein.
Related PathwayTranscription FactorsDruggable Genome Adherens junction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Slug in human kidney cell lysate with Slug antibody at in (A) 1 and (B) 2 µg/ml.
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