Home Antibody All anti-SMO antibodies
| Peptide with sequence C-NLMDTELMDADSD, from the C Terminus of the protein sequence according to NP_005622.1.|
||Lot dependent; please refer to CoA along with shipment
||ELISA: 1:32,000. WB: 0.3-1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens smoothened, frizzled class receptor (SMO)|
|FZD11; Gx; SMOH|
|G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO)|
Hedgehog signaling pathway
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A) TA303075 and B) TA303149 (0.3µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence