Home Antibody All anti-SMAD7 antibodies
Also for SMAD7 (NM_005904)
|Synthetic peptide from human Smad 7 |
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti-Smad7 polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens SMAD family member 7 (SMAD7), transcript variant 1|
|CRCS3; MADH7; MADH8|
Entrez Gene 4092 Human
Entrez Gene 17131 Mouse
Entrez Gene 81516 Rat
|Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFß/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-ß and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFß signaling by interfering with TGFß-mediated phosphorylation of other Smad family members.|
|Transcription FactorsDruggable Genome TGF-beta signaling pathway|
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Western blot analysis of Smad7 expression in Jurkat cell lysate (Lane 1& 2) and 3T3 cell lysate (Lane 3).