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Anti-SMAD3 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA325855 Rabbit Polyclonal Smad3 (Ser213) Antibody (Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human Smad3 around the phosphorylation site of Serine 213
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
Predicted MW Explanation 48kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens SMAD family member 3 (SMAD3), transcript variant 2
Alternative NameHSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3
Database LinkNP_001138574
Entrez Gene 4088 Human
Entrez Gene 17127 Mouse
Entrez Gene 25631 Rat
FunctionSmad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayES Cell Differentiation/IPSCancer stem cellsEmbryonic stem cellsTranscription FactorsDruggable Genome Cell cycleWnt signaling pathwayTGF-beta signaling pathwayAdherens junctionPathways in cancerColorectal cancerMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Smad3 phosphorylation expression in HT29 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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