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Anti-SMAD1 Antibody EP565Y
Also for SMAD1 (NM_005900)
|A synthetic peptide corresponding to residues in human Smad1 was used as immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500-2,000; ICC: 1: 100-250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Rat
|Homo sapiens SMAD family member 1 (SMAD1), transcript variant 1|
|BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1|
|Smad 1 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight Smads have been identified and can be divided in 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. Smad 1, 5 and 8 serve as pathway-restricted Smads for the bone morphogenetic proteins (BMPs) signaling pathway (1). Smad 1 is involved in cell growth, apoptosis, morphogenesis, development and immune response (2). After phosphorylaion by the BMP type 1 receptor kinase Smad1 and co-Smad4 form a heteromeric complex and translocate to the nucleus to regulate transcription of target genes (3). |
Delta-Notch Signaling Pathway
TGF Beta Signaling Pathway
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Western blot - Smad1 antibody [EP435E]; Anti-Smad1 antibody [EP565Y] at 1/500 dilution + HeLa cell lysate.Predicted band size : 52 kDa.Observed band size : 58 kDa .
Immunocytochemistry/ Immunofluorescence - Smad1 antibody [EP435E]; Ab33902, at 1/100 dilution, staining Smad1 in HeLa cells by Immunocytochemistry/Immunofluorescence.