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Home Antibody All anti-SLC4A1 antibodies

Anti-SLC4A1 PHOSPHO Antibody EPR1427Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310854
  • Rabbit Monoclonal antibody against AE1, pY359 (SLC4A1) (Phospho-specific)
100ul $325 3-7 Days
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WB(1)
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Also for SLC4A1 (NM_000342)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding tyrosine 359 of human AE1 was used as an immunogen.
Clone NameEPR1427Y IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000; ICC: 1:100 - 250; FC: 1:20;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens solute carrier family 4 (anion exchanger), member 1 (Diego blood group) (SLC4A1)
Alternative NameAE1; BND3; CD233; DI; EMPB3; EPB3; FR; RTA1A; SW; WD; WD1; WR
Database LinkNP_000333
FunctionThe AE1 (anion exchanger, band 3) protein is expressed in erythrocytes and in the A-type intercalated cells of the kidney distal collecting tubule. In both cell types it mediates the electroneutral transport of chloride and bicarbonate ions across the lipid bilayer, and, in erythrocytes (1). AE1 is phosphorylated on Tyr359 and Tyr404 by Lyn in erythrocytes. Phosphorylation of these residues is necessary for correct localization and recycling of kidney AE1 to the basolateral membrane (2).
Related Pathway

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WB Image
Western blot - Band 3 (phospho Y359) antibody [EPR1427Y]; All lanes : Anti-Band 3 (phospho Y359) antibody [EPR1427Y] at 1/50000 dilution.Lane 1 : Red blood cell lysate, untreated.Lane 2 : Red blood cell lysate treated with pervanadate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 102 kDa.Observed band size : 102 kDa.

 

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