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Home Antibody All anti-SLAMF1 antibodies

Anti-SLAMF1 Antibody 9D1

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320462
  • Rat Anti-Mouse CD150 Purified (100 ug)
100ug $120 3-7 Days
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FC(1)

OriGene Data

Immunogen
Clone Name9D1 Isotype
Species ReactivityMouse Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application *FC Suggested DilutionsFlow, Functional Assay
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameMus musculus signaling lymphocytic activation molecule family member 1 (Slamf1)
Alternative Name4933415F16; AA177906; CD150; CDw150; ESTM51; IPO-3; Slam
Database LinkNP_038758
FunctionThe 9D1 monoclonal antibody reacts with mouse CD150, an ~70 kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T (especially TH1) and B cells and its expression is rapidly upregulated on these cells upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. 9D1 is reported to be an activating antibody.Mouse hematopoietic stem cells (HSC) can be identified using SLAM family markers, such as CD150+CD244-CD48-. For this application we recommend the use of antibody clone mShad150 (cat. 12-1502).
Related Pathway

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FC Image
Staining of C57BL/6 splenocytes with 0.5 ug of Rat IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD150 Purified (filled histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE . Cells in the lymphocyte gate were used for analysis.

 

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