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Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566. [anti-HA]
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RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159. [LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408. [JAK2]
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 Home All anti-SKIL antibodies

Anti-SKIL TrueMAB Antibody Clone 2F6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA800171
  • Purified SKIL (SnoN) mouse monoclonal antibody, Clone 2F6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417307) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF800171
  • Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody,clone 2F6
100ug $450 8-10 Days Add to Shopping Cart
WB(2)
IHC(10)
Gene NameHomo sapiens SKI-like oncogene (SKIL), transcript variant 1
Synonyms:SNO; SnoA; SnoI; SnoN
ImmunogenHuman recombinant protein fragment corresponding to amino acids 307-684 of human SKIL (NP_005405) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2F6 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500~2000, IHC 1:150,
BackgroundThe protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Related Pathway
TGF Beta Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SKIL monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-SKIL mouse monoclonal antibody. (TA800171)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SKIL mouse monoclonal antibody. (TA800171)

 

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