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Home Antibody All anti-SIRT5 antibodies

Anti-SIRT5 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319855
  • Chicken Polyclonal SIRT5 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC434135) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for SIRT5 (NM_001193267)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSIRT5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT5.
Clone NamePolyclonal IsotypeIgY
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
BufferSIRT5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification SIRT5 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens sirtuin 5 (SIRT5), transcript variant 3
Alternative NameSIR2L5
Database LinkNP_001180196
FunctionSIRT5 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.
Related Pathway

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WB Image
Western blot analysis of SIRT5 in human liver tissue lysate with SIRT5 antibody at 1 ug/mL.

 

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