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Anti-SIRT1 PHOSPHO Antibody EPR2849Y
Also for SIRT1 (NM_012238)
|A phospho specific peptide corresponding to residues surrounding serine 47 of human Sir2/SIRT1 was used as an immunogen. This antibody detects Sir2/SIRT1 phosphorylated on ser 47|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 -2000; IHC: 1:250 -500; ICC: 1:100 -250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens sirtuin 1 (SIRT1), transcript variant 1|
|This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. |
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Western blot - SIRT1 (phospho S47) antibody [EPR2849Y]; All lanes : Anti-SIRT1 (phospho S47) antibody [EPR2849Y] at 1/2000 dilution.Lane 1 : 293 cell lysate.Lane 2 : 293 cell lysate treated with LP.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 82 kDa.Observed band size : 82 kDa.