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Anti-SILV TRUEMAB Antibody Clone OTI7E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500425 SILV (Melanoma gp100) mouse monoclonal antibody, clone OTI7E3 (formerly 7E3) 100ul
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CF500425 Carrier-free (BSA/glycerol-free) SILV mouse monoclonal antibody, clone OTI7E3 (formerly 7E3) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human SILV (NP_008859) produced in HEK293T cell.
Clone NameClone OTI7E3 IsotypeIgG2b
Species ReactivityHuman Concentration0.9 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsFLOW 1:100, IHC: 1:150
Predicted MW Explanation 70.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens premelanosome protein (PMEL), transcript variant 3
Alternative NameD12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
Database LinkNP_008859
Entrez Gene 6490 Human
FunctionCould be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Related PathwaySecreted ProteinTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts (10ug) from 4 different cell lines by using anti-SILV monoclonal antibody at 1:200 dilution.
Western blot analysis of extracts (10ug) from a mouse cell line and 3 different mouse tissues by using anti-SILV monoclonal antibody.(1:200)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SILV mouse monoclonal antibody. (TA500425)
HEK293T cells transfected with either RC200663 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SILV antibody(TA500425), and then analyzed by flow cytometry.


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