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Home Antibody All anti-SILV antibodies

Anti-SILV TRUEMAB Antibody clone 8A4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500402
  • anti-SILV (Melanoma gp100) mouse monoclonal antibody, clone 8A4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402062) , 20ug Explanation
100ul 379 In Stock
CF500402
  • Carrier-free (BSA/glycerol-free) SILV mouse monoclonal antibody,clone 8A4
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IF(2)
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Also for SILV (NM_006928)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human SILV expression vector
Clone Nameclone 8A4 IsotypeIgG2b
Species ReactivityHuman, Dog, Rat, Monkey Concentration1.15 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:1000
Predicted MW Explanation 70.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens premelanosome protein (PMEL), transcript variant 3
Alternative NameD12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
Database LinkNP_008859
Entrez Gene 6490 Human
Entrez Gene 362818 Rat
Entrez Gene 710921 Monkey
Entrez Gene 481102 Dog
FunctionCould be a melanogenic enzyme. Could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity
Related PathwaySecreted ProteinTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SILV (RC200663, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SILV .
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SILV monoclonal antibody.
IF Image
Anti-SILV mouse monoclonal antibody (TA500402) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SILV (RC200663).
IF Image
Immunofluorescent staining of A549 cells using anti-SILV mouse monoclonal antibody (TA500402).

 

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